Serum 16


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Serum 16 | Rapid Renewal Complex

Containing LG-Retinex—a proprietary GAG-enhanced encapsulation of retinol and retinaldehyde—Serum 16 is the closest thing to prescription strength age defiance without a prescription.


Increases cellular turnover
Reduces the appearance of fine lines/wrinkles Improves skin texture and tone
Brightens the look of age spots and discoloration Boosts vital hydration
Helps “lift” away visible irritation and signs of damage Less irritation/redness than traditional retinol products


Normal to dry
Imbalanced/aging skin,
crow’s feet/fine lines/medium to deep wrinkles Hyperpigmentation
Sun damage


Retinol: The gold standard in anti-aging. A form of Vitamin A that increases cell turnover.
Retinal (Retinaldehyde): More bioactive form of Vitamin A. Only one step from prescription-only retinoic acid in conversion pathway. Increased age defiance.
Glycosaminoglycans (GAGs): Help transport retinol and retinal to correct skin receptor sites. Phospholipids: Protect retinol and retinal from oxidation for maximum potency.
Sodium PCA: A high-performance humectant and component of skin’s NMF (natural moisturizing factor).
Sodium Hyaluronate: Binds 1000 times its own weight in water. Naturally found in the tissue. Squalane: Emollient; regenerative; nourishing. Source: olive (Olea europaea).
Tocopheryl Acetate: A form of Vitamin E; antioxidant.
Sodium Lactate: Highly moisturizing; component of NMF (natural moisturizing factor).

Directions for Use:

Home Care: Apply a pea-sized amount to clean skin as tolerated every 1-3 nights, working up to nightly use. May be followed with moisturizer if additional hydration is needed. Daily sunscreen use is mandatory. Do not apply to eyelids.
Clinic Care: May use as a Vitamin A treatment.

All Ingredients:

Aqua, Hamamelis Virginiana (Witch Hazel) Water, Tocopheryl Acetate, Sodium Lactate,
Glycerin, Galactoarabinan, Sodium PCA, Phospholipids, Ethylhexylglycerin, Xanthan Gum, Glycosaminoglycans, Leuconostoc/Radish Root Ferment Filtrate, Retinol, Retinal, Tetrasodium EDTA, Proline (L), Sodium Hyaluronate, Sodium Hydroxymethylglycinate, Squalane, Aniba Rosaeodora (Rosewood) Wood Oil, Lavandula Angustifolia (Lavender) Oil, Helianthus Annuus (Sunflower) Seed Oil, Cassia Angustifolia Seed Polysaccharide, Dimethicone, Sorbitol, Polysorbate 20, Potassium Sorbate